KETOROLAC TROMETAMOL—A NEW NON-OPIOID ANALGESIC
نویسندگان
چکیده
منابع مشابه
Non-opioid analgesic poisoning.
Since the first cases of severe and fatal liver damage were reported in 1966,1,2 overdose of paracetamol has become the cause of 100–200 deaths in the UK each year.3 Paracetamol toxicity remains the leading cause of fulminant hepatic failure in the UK and is a common reason for liver transplantation.4,5 Knowledge of the toxic mechanism (Fig 1) has led to effective antidotes which provide substr...
متن کاملKetorolac, a new non-opioid analgesic: a single-blind trial versus buprenorphine in pain after orthopaedic surgery.
A randomized single-blind, double-observer trial was performed to evaluate the efficacy of a new non-steroidal anti-inflammatory analgesic drug, ketorolac, in the treatment of post-orthopaedic surgery pain. Sixty patients with moderate to severe pain were studied; 30 patients were treated with ketorolac at a dose of 30 mg intramuscularly up to 4-times a day, whilst the other 30 patients receive...
متن کاملKetorolac tromethamine: A nonsteroidal anti-inflammatory analgesic
This case report describes a general anesthetic where ketorolac tromethamine was used instead of a narcotic. The patient was a 37-year-old male, ASA II category, who underwent general anesthesia for a cholecystectomy. The drug is discussed in terms of preoperative, intraoperative, and immediate postoperative effects. During the preoperative phase, no effect was demonstrated. Intraoperatively, t...
متن کاملManagement of opioid analgesic overdose.
Copyright © 2012 Massachusetts Medical Society. Opioid analgesic overdose is a preventable and potentially lethal condition that results from prescribing practices, inadequate understanding on the patient’s part of the risks of medication misuse, errors in drug administration, and pharmaceutical abuse.1,2 Three features are key to an understanding of opioid analgesic toxicity. First, opioid ana...
متن کاملAnalgesic efficacy and safety of ketorolac after photorefractive keratectomy. Ketorolac Study Group.
PURPOSE The analgesic efficacy and safety of topical ketorolac tromethamine 0.5% ophthalmic solution (Acular) in photorefractive keratectomy was compared to its vehicle. METHODS Double-masked, multicenter, study of 200 patients dosed with 1 drop of study medication (ketorolac or vehicle) in the operated eye immediately after surgery (eye patched), with four-times daily dosing for the next 3 d...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1990
ISSN: 0007-0912
DOI: 10.1093/bja/65.4.445